研究業績
Biochemical and Biophysical Research Communications Volume 796, 153160 (2026)
NVL2-interacting protein CWF19L2 is required for debranching of intron-derived lariat RNAs
著者
Oshima R, Izumikawa K, Yamazaki R, Iwakawa Y, Tamura M, Shida T, Miyao S, Nagahama M
キーワード
CWF19L2, NVL2, splicing, debranching
カテゴリ
原著論文
Abstract
•NVL2 interacts with the spliceosome-associated protein CWF19L2.
•CWF19L2 interacts with ILS, RNA-debranching factors, and MTR4-RNA exosome complex.
•CWF19L2, CWF19L1, and DBR1 are required for lariat RNA debranching.
•Super-resolution imaging reveals close colocalization of DBR1, CWF19L1, and CWF19L2.